OCREVUS® Infusion Therapy
OCREVUS infusion therapy is an IV medication administered as a treatment for Multiple Sclerosis (MS). OCREVUS infusion therapy may help prevent relapses in patients with MS or slow disease progression and improve daily life.
About OCREVUS® Infusion Therapy
OCREVUS infusion therapy (ocrelizumab) is an IV therapy used to treat patients with both Relapsing MS (RMS) and Primary Progressive MS (PPMS). OCREVUS is a biologic medication and contains proteins that target specific areas of the immune system.
In people with Multiple Sclerosis, the immune system inappropriately attacks the sheath that covers nerves in the brain and spinal cord. This sheath is called Myelin, and when it is damaged it causes disruptions in the communication signals sent throughout the body. The current understanding of this process is that B cells play a key role in triggering these attacks.
OCREVUS infusion therapy targets B cells and attaches to the B cells and destroys them before they can cause damage to the nerves.
OCREVUS® Infusion Therapy for MS
OCREVUS infusion therapy was approved by the FDA in 2017 to treat patients with Relapsing MS (RMS) and Primary Progressive MS (PPMS). It is the first medication approved to treat PPMS. Unlike other medications for MS that need to be administered more frequently, patients receiving OCREVUS infusions only require 3 infusions in the first year of treatment.
In a clinical study, about 83% of OCREVUS patients with RMS had no relapses, while the number of total relapses was cut almost in half (46%).1 OCREVUS infusion therapy patients with PPMS were shown to be 24% less likely to have disability progression while on the medication. This means patients were 24% less likely to notice worsening MS symptoms, including numbness, loss of coordination, speech and swallowing problems, memory loss, visual impairment, and bowel and bladder dysfunction, and muscle weakness.
The out-of-pocket OCREVUS cost will vary depending on your insurance coverage. If you have Medicare Part B or Medicaid, some of the OCREVUS cost may be partially covered.
Patients with commercial insurance may qualify for the OCREVUS Co-pay Program which can help cover the OCREVUS cost. For more information on OCREVUS cost and financial resources, you may visit https://www.ocrevus.com/patient/financial-support/assistance-options.html.
No patient should go without necessary treatment due to financial limitations. If you have questions about financial assistance opportunities or OCREVUS cost, contact a member of our FlexCare team or your referring provider.
What to Expect During OCREVUS® Infusion Therapy
If your provider has prescribed OCREVUS infusion therapy as a Multiple Sclerosis medication, you will receive 2 doses six months apart. The first dose of OCREVUS is administered as 2 infusions that last around 2.5 hours. Your MS infusion may take longer depending on a variety of factors.
OCREVUS Side Effects
Most patients tolerate OCREVUS well. The most commonly reported OCREVUS side effects include skin and upper respiratory tract infections and infusion reactions (itching, redness, headache, nausea, throat irritation, fatigue, and dizziness).
There is a possibility of Hepatitis B reactivation during OCREVUS treatment. Before starting OCREVUS, your provider will perform a Hepatitis B screening to rule out active HBV. If you have had HBV in the past, your provider will monitor your risk throughout your course of treatment.
If you have concerns about OCREVUS side effects, contact your referring provider.
OCREVUS Infusion Therapy at FlexCare
Before your OCREVUS infusion, it’s important to take care of your overall health. Prepare for your visit to have a more comfortable infusion experience. It’s recommended to wear comfortable clothes and a shirt with loose-fitting sleeves. Make sure to arrange for transportation in advance and bring any needed items, such as your laptop or phone, with you to your appointment.
Find an infusion center near you.
Getting Started With Infusion Therapy
If you have Relapsing or Primary Progressive MS, talk with your provider about an OCREVUS infusion therapy referral for FlexCare Infusion Centers. We offer convenient evening and weekend appointment times, comfortable infusion suites, and walk-up parking for OCREVUS patients.
If you have any questions, you can also contact FlexCare directly. We look forward to helping you soon.
If you have any questions about OCREVUS or infusion therapy, contact us directly. We look forward to helping you on your journey to better health.